Toward a History of Epistemic Things: Synthesizing Proteins in the Test Tube (Writing Science) by Hans-Jörg Rheinberger
Toward a History of Epistemic Things: Synthesizing Proteins in the Test Tube (Writing Science) by Hans-Jörg Rheinberger PDF, ePub eBook D0wnl0ad
A central concern of the book is the basic question of how novelty is generated in the empirical sciences. In addressing this question, the author brings French poststructuralist thinking—notably Jacques Derrida’s concepts of “différance” and “historiality”—to bear on the construction of epistemic things. Historiographical perspective shifts from the actors’ minds to their objects of manipulation.
These epistemological and historical issues are illuminated in a detailed case study of a particular laboratory, that of the oncologist and biochemist Paul C. Zamecnik and his colleagues, located in a specific setting—the Collis P. Huntington Memorial Hospital of Harvard University at the Massachusetts General Hospital of Boston. The author traces how, between 1945 and 1965, this group developed an experimental system for synthesizing proteins in the test tube that put Zamecnik’s research team at the forefront of those who led biochemistry into the era of molecular biology.
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